Metabolic dysfunction-associated steatohepatitis (MASH), previously known as non-alcoholic steatohepatitis (NASH), is a progressive liver condition linked to obesity, insulin resistance, and high cholesterol. It can lead to serious complications such as progressive liver disease and liver cancer.
Current treatment options are limited and often rely on lifestyle changes like diet and exercise. While some medications exist, they don’t work for everyone, highlighting the need for new therapies.
This clinical trial is evaluating a potential new injectable medication designed to activate two important pathways in the body that help regulate metabolism, reduce liver fat, and improve insulin sensitivity. These pathways are known to play a role in managing metabolic disorders and liver inflammation.
Requirements
- Male or Female
- Healthy
- 18 - 55 years old
- BMI 22 - 35 kg/m2
- Not taking any medications
- Non-smoker
Start dates
17 Nov 2025 to 23 Dec 2025
Study visits
7 nights, 5 clinic visits