The Violet Study

Currently Recruiting

2 Nov 2026 to 6 Jan 2027

Up to $17,750

Sydney, Australia

This study is looking at an investigational oral drug for people living with obesity or overweight. 

Obesity is a chronic disease that is estimated to affect ~880 million adults globally.  Adults living with obesity and overweight are at higher risk for other health problems. For some people, medicines are recommended to support weight management; however, more treatment options are needed to treat this chronic disease.  The investigational drug is an oral tablet that is designed to help people feel full sooner and reduce feelings of hunger, which may help people eat less over time. 

The start date for this study is flexible. If you pass the initial screening, the study coordinator will work with you to schedule your exact dates.
Please note that you can only be admitted between Sunday and Thursday.

Apply now Speak with us 1300 318 660

What to expect?

  • Participation in a monitored clinical environment 
  • Support from a professional medical team 
  • Compensation for your time and commitment will be provided to participants who complete the full study 

Trial details

Study medication

The study drug or placebo will be given as an oral tablet

Study duration

  • 30 nights in clinic – split into 3 stays
  • At home dosing for 5 days
  • 5 follow-up visits

Additional eligibility

  • Male or female aged 18-60, inclusive of all genders 
  • Weigh at least 70 kg with a BMI (body mass index) between 27 and 40 kg/m2 
  • Stable body weight (≤5% change within 3 months) 
  • Non-smoker, or smoking 10 or less cigarettes (or equivalent) per day, and agrees to abstain for the duration of the study  
  • Not pregnant or breastfeeding   
  • Willing to follow contraception guidelines (If applicable)  
  • Willing and able to attend all study visits and follow instructions 
  • Other eligibility criteria apply     

Ethics

An independent ethics committee has approved this clinical trial.

Are you a match?

Age

18 - 60 years old

Remuneration

Up to $17,750 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male, Female, Female (Post-menopausal) or Female of non-childbearing potential

BMI

BMI 27 - 40 kg/m2

Commitment

30 nights, 5 clinic visits

Medical condition

Not taking any medications

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information


Consent to Information Use and Future Contact