The Metabolic Balance Study

Currently Recruiting

9 Aug 2026

Up to $5,400

Melbourne, Australia

Obesity is a major global health concern, affecting millions and leading to serious complications. Current treatments often involve invasive procedures or medications with significant side effects.

Apply now Speak with us 1300 194 547

Join our clinical trial

We are evaluating the safety, tolerability, and effectiveness of a potential new treatment option for obesity, an oral capsule that delivers a drug for the treatment of  type 2 diabetes and obesity. This potential treatment offers an alternative to injections, aiming to improve treatment convenience and patient experience.

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Why participate?

By joining this study, you will contribute to research exploring a novel, non-injectable or oral obesity treatment. Your participation helps advance medical science, potentially leading to more accessible and safer weight management options.

As a healthy volunteer, you will help researchers understand how study drug is processed in the body and its potential benefits for obesity treatment. Your involvement is a crucial step in developing future treatments.

Study schedule

 

Intake 1 In-clinic stay:

9 August 2026 – 14 August 2026

 Follow-up visits:

17 August 2026– 14 September 2026
Approx. 5 visits during this period
Intake 2 In-clinic stay:

10 August 2026 – 15 August 2026

 Follow-up visits:

18 August 2026– 15 September 2026
Approx. 5 visits during this period

Study dates are subject to change. Our team will confirm details with you during the screening process.

Trial details

Study medication

Administered via oral capsule or subcutaneous injection.

Additional eligibility

  • Not taking any prescription medication (except for contraception)
  • Non-smoker or smoking less than 2 cigarettes or equivalent per day.
  • Participants must not have experienced more than a 5% loss in body weight within the 2 months prior to screening.
  • Non-smoker or smoking less than 2 cigarettes or equivalent per day. 

Ethics

An independent ethics committee has approved this clinical trial

Study duration

  • 5-night stay
  • 5 follow-up visits

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $5,400 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male, Female, Female (Post-menopausal) or Female of non-childbearing potential

BMI

BMI 19 - 32 kg/m2

Commitment

5 nights, 5 clinic visits

Medical condition

Not taking any medications

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




The phone number you have entered does not appear to be a valid active Australian phone number. Please check your details and enter a valid Australian phone number starting with +61

Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information


Consent to Information Use and Future Contact