The Strive Study
Recruitment Closed
$6,337
Minneapolis, United States
At Nucleus Network, we lead the way in advancing medical research through clinical trials that explore new investigational medicines aimed at improving lives across a wide range of health conditions.
We’re currently inviting healthy volunteers to take part in a clinical study evaluating a potential new treatment for cystic fibrosis.
Join our clinical trial
The study will look at how study drug SION-451 interacts with midazolam, a commonly used medication. Midazolam is not being used for anxiety or sedation in this study, but rather to help determine whether SION-451 affects how similar drugs are processed in the body.
- Twice daily dosing
- SION-451 co-administered with midazolam
Trial details
Purpose:
This study is a drug-drug interaction (DDI) study, which means it evaluates the effect that one drug has on the breakdown of another drug. This study will investigate whether there is the potential for a drug-drug interaction between study drug SION-451 and midazolam commonly used for anxiety or sedation.
Commitment
- 1 Inpatient Stay 12 nights/ 13 days
- Admit 2/16/26-2/28/26
- End of study phone call 3/6/26
Meal Requirements
Foods to avoid: Avoid cruciferous vegetables, charcoal-grilled meats, and poppy seeds for 48 hours before Day 1 through the entire trial
Are you a match?
Age
18 - 55 years old
Remuneration
$6,337 *with screening reimbursement. Please see T&Cs.
Gender
Male or Female
BMI
BMI 18 - 32 kg/m2
Commitment
12 nights