The Relief Research Study

Currently Recruiting

19 Jul 2026

$4,170

Brisbane, Australia

Pain is common, and for many people, current treatments don’t always work well or can cause problems. Some pain medicines rely on opioids, which can lead to side effects or dependency.

This study is testing Wafermine, a new type of pain medicine in healthy volunteers to improve future patient outcomes. Wafermine is a small wafer placed under the tongue, where it dissolves quickly. It does not require needles and does not rely on opioids.

The active medicine, ketamine, has been safely used by doctors for over 50 years at low doses to treat pain. This new wafer form is designed to potentially help the medicine work faster and more smoothly by being absorbed under the tongue instead of going through the stomach and liver first.

By taking part in this study, you can play an important role in helping researchers better understand how potential new treatments to manage pain work.

Apply now Speak with us 1300 332 135

Join our clinical trial

The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee. It is not known whether the study drug may cause unexpected, serious, or life-threatening side effects. While these are considered unlikely, you will be carefully monitored throughout the study and provided with prompt treatment if any such effects occur.

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions.

Why participate?

  • Participation in a monitored clinical environment
  • Study visits scheduled
  • Support from a professional medical team
  • Reimbursement for your time and commitment

Study schedule

 

Intake 1 In-clinic stay:

19 July 2026 – 26 July 2026

 Phone call:

29 July 2026

Study dates are subject to change. Our team will confirm details with you during the screening process.

Trial details

Study duration

  • 7 nights stay
  • 1 phone call

Study medication

Administered as a dissolvable wafer.

Ethics

An independent ethics committee has approved this clinical trial.

Are you a match?

Age

18 - 65 years old

Remuneration

$4,170 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male or Female

BMI

BMI 18.5 - 30 kg/m2

Commitment

7 nights

Medical condition

Not taking any medications

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
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You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact