The Muscle Health Study
Recruitment Closed
7 Oct 2025 to 8 Nov 2025
Up to $16,260
Melbourne, Australia
The purpose of this study is to assess the safety and clinical pharmacology effect of a potential new treatment targeting muscle degeneration. This potential new treatment focuses on a specific enzyme crucial for cellular energy production, aiming to bolster muscle health and strength by raising NAD levels – a vital molecule for cellular energy.
Join our clinical trial
Study Objective
The purpose of this study is to assess the safety and clinical pharmacology effect of a potential new treatment targeting muscle degeneration. This potential new treatment focuses on a specific enzyme crucial for cellular energy production, aiming to bolster muscle health and strength by raising NAD levels—a vital molecule for cellular energy.
The study drug is designed to activate the NAMPT enzyme, which helps boost NAD levels. NAD levels are essential for good cellular energy and function. This study drug could potentially help treat muscle degeneration disorders like Duchenne Muscular Dystrophy and sarcopenia, improving muscle condition and performance.
NAD is found in every cell and is vital to energy metabolism. It also helps with DNA repair, gene expression, and stress response. However, NAD levels naturally decrease with age, leading to less energy and more cellular stress. Increasing NAD levels may help boost energy and reduce some aging symptoms.
Why participate?
This study is an opportunity to contribute to the development of a treatment that could improve the lives of those with muscle-degenerative diseases. Your participation as a healthy volunteer could be instrumental in advancing a treatment that may significantly improve the quality of life for individuals affected by these conditions.
Trial details
Study medication
Administered via oral tablet.
Ethics
This is the first time the study drug is being administered to humans, so there may be unknown risks involved. However, this clinical trial has been carefully designed to minimize risks for participants. Before you decide to participate, you will receive detailed information about the trial, including its risks and our mitigation strategies. You will also have an appointment with one of our doctors, who will be happy to answer any questions you may have.
Additional eligibility
Weight above 50kg at screening
Are you a match?
Age
18 - 59 years old
Remuneration
Up to $16,260 *with screening reimbursement.
Full details outlined in consent form.
Gender
Male or Female
BMI
BMI 18 - 32 kg/m2
Commitment
32 nights, 1 clinic visit
Medical condition
Not taking any medications