The Celest Study

Currently Recruiting

17 Nov 2026

Up to $13,560

Sydney, Australia

We’re launching a new clinical study exploring an investigational treatment designed for people living with hypoparathyroidism. This rare condition can disrupt the body’s calcium balance, often leading to muscle cramps, tingling, fatigue, and other daily challenges. 

Apply now Speak with us 1300 814 852

Join our clinical trial

Our study focuses on a potential new therapy that aims to restore healthier parathyroid hormone function and improve overall quality of life. By participating, volunteers may help advance research that could lead to new treatment options for the broader hypoparathyroidism community. 

This new treatment is being developed because current options for hypoparathyroidism have some major limitations. Right now, most people have to take large amounts of calcium and active vitamin D every day to keep their blood calcium levels stable. While these supplements can help prevent low calcium, they don’t replace the parathyroid hormone (PTH) that the body is missing. As a result, this approach can be hard to manage and may cause other issues over time. 

What to expect?

  • Participation in a monitored clinical environment 
  • Study visits scheduled  
  • Support from a professional medical team 
  • Reimbursement for your time and commitment 

Study schedule

 

Intake 1 In-clinic stay:

17 November 2026 – 14 December 2026

 Follow-up visits:

22 December 2026

Study dates are subject to change. Our team will confirm details with you during the screening process.

Trial details

Study duration

  • 27 nights in-clinic
  • 1 follow-up visit

Study medication

The study drug will be administered as an oral capsule or oral tablet

Ethics

An independent ethics committee has approved this clinical trial.

This is a first-in-human (FIH) study, meaning it is the first time the potential treatment is being tested in people. The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee. It is not known whether the study drug may cause unexpected, serious, or life-threatening side effects. While these are considered unlikely, you will be carefully monitored throughout the study and provided with prompt treatment if any such effects occur. 

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions.

Additional eligibility

  • Prescription medications must be complete 7 days prior to admission 
  • Non-smokers or smoking less than 5 cigarettes per week  
  • Not pregnant or breastfeeding   
  • Willing to follow contraception guidelines (If applicable)  
  • Willing and able to attend all study visits and follow instructions   

Are you a match?

Age

21 - 60 years old

Remuneration

Up to $13,560 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male or Female

BMI

BMI 18 - 32 kg/m2

Commitment

27 nights, 1 clinic visit

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information


Consent to Information Use and Future Contact