The Bio Defence Study

Currently Recruiting

5 Oct 2026

Up to $6,260

Melbourne, Australia

We are conducting a clinical trial to evaluate a potential new antibiotic in healthy adult volunteers. This study aims to assess the safety, tolerability, and how the body processes this medication. 

The investigational treatment is being developed to combat antimicrobial resistance (AMR) by targeting dangerous bacteria. 

Apply now Speak with us 1300 476 507

Join our clinical trial

This clinical trial has been carefully designed to minimize risks for participants. Before you join, you will receive detailed information about the trial, its risks, and our strategies to mitigate them. You will also have an appointment with one of our doctors, who will be happy to answer any questions you may have. 

As a participant, you’ll receive the study medication and undergo assessments to monitor how your body responds. Your involvement will provide essential data that can help guide future research.

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Why participate?

  • Contribute to scientific research that may lead to new antibiotic treatments. 
  • Help researchers understand how the medication is absorbed and processed in the body. 

Study schedule

 

Intake 1 In-clinic stay:

5 October 2026 –17 October 2026

 Follow-up visits:

22 October 2026
Intake 2 In-clinic stay:

25 October 2026 –6 November 2026

 Follow-up visits:

11 November 2026

Study dates are subject to change. Our team will confirm details with you during the screening process.

Trial details

Study duration

  • 12 nights stay
  • 1 follow-up visit

Study medication

Administered via intravenous infusion (a small canula which is placed in the vein to deliver the study drug) or PICC line.

Ethics

An independent ethics committee has approved this clinical trial. 

Additional eligibility

  • Weight between 55-100kg
  • Non-smokers and have not smoked within 1 month prior to dosing

Are you a match?

Age

18 - 55 years old

Remuneration

Up to $6,260 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male, Female, Female (Post-menopausal) or Female of non-childbearing potential

BMI

BMI 19 - 30 kg/m2

Commitment

12 nights, 1 clinic visit

Medical condition

Not taking any medications

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




The phone number you have entered does not appear to be a valid active Australian phone number. Please check your details and enter a valid Australian phone number starting with +61

Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information


Consent to Information Use and Future Contact