Participate in a Trial

Minneapolis Clinical Trials

Nucleus Network Minneapolis (formerly known as Prism Clinical Research) is conveniently located in the heart of the Minneapolis-St. Paul metropolitan area. We conduct FDA-approved clinical trials on behalf of drug and device manufacturers, academic and private physicians as well as other researchers across Minnesota.

We have been performing clinical studies since 2005, with the cooperative effort of our highly experienced staff, volunteers, and our pharmaceutical & academic partners. It takes the coordination of many people and organizations to safely and successfully navigate the clinical trial process and Nucleus Network is at the center of those efforts.

We are actively recruiting for new paid clinical trials, with new studies opening up all the time. Not all studies are listed on our website, so please call us at (651) 641-2900 to find out more about current and upcoming studies or register your interest here.

We perform mostly Phase 1 clinical trials, with a focus on healthy volunteer trials (participants with no medical conditions) and hepatic & renal trials (participants with liver & kidney impairments). No matter your health status, you can register your interest and we will be in touch if there is a clinical trial that you might be able to participate in.

Due to COVID-19 restrictions, we currently only allow participants who live within 300 miles of our clinic.

We look forward to welcoming you at our clinic soon!

  • Study name 2035 Study
    Eligibility
    • Biological Sex Healthy males or females
    • Contraception Requirements Men must have had a vasectomy, women must be of non-childbearing potential
    • Age 18 - 65 years old
    • BMI 18 -32
    • Weight >110 llbs
    • Medications Able to avoid taking any medications 2 weeks prior to first drug administration
    • Smoking History Non-smoker/non-vaper
    Status Currently Recruiting
    Overnight stays 3 x 5 nights nights
    Outpatient visits 1 visits
  • Study name 1914 Study (Healthy)
    Eligibility
    • Biological Sex Healthy males or females
    • Medication Considered on case by case basis
    • Age 75 years or older
    Status Currently Recruiting
    Overnight stays 0 nights
    Outpatient visits 1 visits
  • Study name 2019 Study Healthy (SAD)
    Eligibility
    • Biological Sex Healthy males or females
    • Age 18 - 64 years old
    • BMI 18 -32
    • Medication Not taking any (hormonal birth control is allowed)
    • Smoking History Non-smokers
    Status Currently Recruiting
    Overnight stays 0 nights
    Outpatient visits 5 visits
  • Study name 2019 Study (Healthy) (MAD)
    Eligibility
    • Biological Sex Healthy males or females
    • Age 18 - 64 years old
    • BMI 18 - 32
    • Medication Not taking any (hormonal birth control is allowed)
    • Smoking History Non-smokers
    Status Currently Recruiting
    Overnight stays 0 nights
    Outpatient visits 10 visits
  • Study name 2022 Study (Parts 3 & 4)
    Eligibility
    • Biological Sex Healthy males or females
    • Age 18 - 55 years old
    • BMI 17.5 - 30.5
    • Smoking History Occasional smokers allowed, but must refrain during study
    • Contraception Must agree to use
    Status Currently Recruiting
    Overnight stays 5 nights
    Outpatient visits 1 phone call visits
  • Study name 2028 Study (SAD)
    Eligibility
    • Biological Sex Healthy males or females
    • Age 18 - 55 years old
    • BMI 18 - 30
    • Weight Under 220 lbs.
    • Smoking History Non-smokers or social smokers (less than 5 cigarettes per week)
    • Medication Not taking any prescribed medications (hormonal birth control allowed)
    • Legal Not under any administrative or legal supervision
    Status Currently Recruiting
    Overnight stays 2 nights
    Outpatient visits 1 visits
  • Study name 2037 Study (MAD)
    Eligibility
    • Biological Sex Healthy males or females (of non -child bearing potential)
    • Age 18 - 55 years old
    • BMI 17.5 - 30.5
    • Weight > 110 lbs
    • Smoking History Must be able to abstain from tobacco/nicotine use 24 prior to admission and throughout study
    Status Currently Recruiting
    Overnight stays 2 x 3 night stay & 1 x 11 night stay nights
    Outpatient visits 3 visits
  • Study name 2037 Study (SAD)
    Eligibility
    • Biological Sex Healthy males or females (of non-child bearing potential)
    • Age 18 - 55 years old
    • BMI 17.5 - 30.5
    • Weight > 110 lbs
    • Smoking History Must be able to abstain from tobacco/nicotine use 24 prior to admission and throughout study
    Status Currently Recruiting
    Overnight stays 11 nights
    Outpatient visits 5 visits
  • Study name 2039 Study
    Eligibility
    • Biological Sex Males or Females
    • Age 18 - 45 years old
    • BMI ≥ 35.0
    • Waist Circumference ≥38.0 inches for males and ≥33.0 inches for females
    • Smoking History Non-smoker, non vaper or smoke < 5 cigarettes per week
    • Claustrophobia Must not be claustrophobic or have an intolerance of small spaces
    Status Currently Recruiting
    Overnight stays 17 nights
    Outpatient visits 3 visits

If you are looking for a paid clinical trial near you, Nucleus Network Minneapolis is the place to be. We are conveniently located near the center of the Twin Cities - you can find directions to our clinic here.

You can find more information about our hepatic clinical trials here. For these studies we require participants with mild to severe liver failure.

We also have renal clinical trials, for which we require participants with mild to severe kidney failure.

Check your eligibility in 2 minutes