The Skin Barrier Study

Currently Recruiting

20 Jan 2026 to 11 Feb 2026

Up to $5,470

Melbourne, Australia

This study is exploring a potential new treatment designed to reduce inflammation and improve skin health in people living with chronic conditions like psoriasis and hidradenitis suppurativa. The goal is to better understand how this therapy works in the body—how it’s processed, tolerated, and whether it can offer meaningful relief. By participating, you’ll help researchers shape future treatments that are more effective, inclusive, and designed for real life.

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Join our clinical trial

As a first in human study, this trial has been carefully designed with strict safety protocols. Before participating, you will be given detailed information about the study, its procedures, and how risks are managed. You’ll also meet with one of our doctors to discuss any questions you may have.

Why participate?

  • Help researchers develop better skin inflammatory conditions, for everyone.
  • Be part of early-stage research that could benefit people who are struggling with skin conditions, such as psoriasis.

Trial details

Study medication

Administered via an oral solution or oral tablet.

Ethics

An independent ethics committee has approved this clinical trial. 

Additional eligibility

  • Non-smokers or smoking no more than 5 cigarettes per day, OR 2 chews of tobacco per day

Study duration

A total of 9 nights in clinic, split across 3 short clinic
stays, 1 follow-up visit

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $5,470 *with screening reimbursement. Please see T&Cs.

Gender

Male or Female (Post-menopausal)

BMI

BMI 18 - 32 kg/m2

Commitment

9 nights, 1 clinic visit

Medical condition

Not taking any medications

Register Your Interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




The phone number you have entered does not appear to be a valid active Australian phone number. Please check your details and enter a valid Australian phone number starting with +61

Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733 or schedule a call.


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact