The Shield Study

Currently Recruiting

23 Apr 2026 to 14 Aug 2026

Up to $13,000

Brisbane, Australia

We are conducting a clinical trial with healthy participants to evaluate a new investigational monoclonal antibody treatment for inflammatory conditions. The study drug is administered via injection and is being tested for safety, tolerability, and how the body processes it.

Apply now Speak with us 1300 417 294

Join our clinical trial

This is a multi-part, Phase 1, first-in-human (FIH) study. It includes single-dose and multiple-dose groups, with a group specifically for Japanese participants.

Before participating, you’ll meet with a study doctor to discuss the study and receive detailed information. This is the first time this investigational treatment is being tested in humans. The study has been carefully designed to minimize risks and includes close medical monitoring. You’ll have time to ask questions and decide if participation is right for you.

Why participate?

  • Contribute to early-stage research that may support future treatments for inflammatory diseases. 
  • Help researchers understand how the investigational drug behaves in different populations. 
  • Play a key role in evaluating how ethnicity and dosing frequency affect drug activity. 

As a participant, you’ll receive the study medication and undergo assessments to monitor how your body responds. Your involvement will provide essential data that can help guide future research. 

Trial details

Study duration

  • 4 nights stay
  • 23 follow-up visits

Study medication

Administered via a subcutaneous injection.

Additional eligibility

• Weight between 40-120 kg
• Non-smokers or smokers up to 10 per day

Ethics

Approved by an independent ethics committee.

Are you a match?

Age

18 - 55 years old

Remuneration

Up to $13,000 *with screening reimbursement. Please see T&Cs.

Gender

Male, Female or Female (Post-menopausal)

BMI

BMI 18 - 32 kg/m2

Commitment

4 nights, 23 clinic visits

Register Your Interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
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You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact