The Headline Trial

Currently Recruiting

26 Mar 2026

Up to $27,460

Melbourne, Australia

We’re currently looking for adults aged 18 to 65 who are experiencing androgenetic alopecia (AGA), also known as pattern hair loss, to take part in The Headline Trial.

Hair loss is common and can affect both men and women. This clinical study is investigating new approaches that may help shape future treatment options.

You don’t need a formal diagnosis to get started. If you think you may have AGA, you can begin with a quick pre-screen. This helps us assess whether you may meet the initial study requirements. Completing the pre-screen doesn’t guarantee enrolment, but it’s an important first step in seeing whether the study may be suitable for you.

By getting involved, you’ll be contributing to research that aims to improve future options for people affected by hair loss.

Join our clinical trial

We’re currently seeking participants for a clinical trial investigating Androgenetic Alopecia (AGA)—commonly known as pattern hair loss.

You do not need a formal AGA diagnosis to attend. If you suspect you have AGA, you’re welcome to screen, as long as you meet the other eligibility criteria.

Why participate?

Hair loss is common, affecting both men and women. These clinical studies aim to explore new approaches that may support future treatment options. While the main goal is to understand safety and tolerability, your participation helps shape the future of hair loss research. 

What stage of hair loss are we looking for?

Use the guide below to see if your hair loss matches what researchers need for this study.

Find your stage

We’re specifically looking for these patterns:

Stage III Vertex

When you look down at the top of your head, you can clearly see your scalp at the crown. Your hairline has receded at the temples. There’s visible thinning where there used to be coverage.

Stage IV

Your hairline has receded significantly. The hair on your crown is sparse or minimal. There’s still a band of hair connecting the sides, but both the front and top show clear scalp visibility.

Stage IVa

Similar to Stage IV but with more pronounced frontal hair loss. The receding has progressed further at the front, while the crown shows noticeable thinning. The separating band of hair is still present but less dense.

Stage V

The hair loss has progressed—larger areas of visible scalp, the band of hair between front and back is getting narrower and less dense, and the thinning has become more pronounced overall. The areas of hair loss at the front and crown are larger and closer to connecting.

The Norwood Scale

Slide image 1

Trial details

Additional eligibility

You may be eligible if you:

  • Weigh over 60kg.
  • Are experiencing male or female pattern hair loss  
  • Men: thinning at the crown or a receding hairline  
  • Have had hair loss for 12 months or more 
  • Are not experiencing sudden or unexplained shedding

You won’t be eligible if you:

  • Have hormone-related conditions like hyperprolactinemia or prolactinoma
  • Used hormone replacement therapy (HRT) in the 6 months before screening
  • Have ever had:
    • A hair transplant
    • Microneedling, laser, or surgical scalp treatments
  • Have any other scalp conditions besides AGA, including:
    • Alopecia areata
    • Scarring hair loss (e.g. lichen planopilaris, folliculitis decalvans)
    • Lupus, psoriasis, or severe dandruff affecting the scalp
    • Fungal or active scalp infections
    • Any other inflammatory or scarring scalp condition

Study duration

Option 1:

  • 4 sets of 3 overnight stays (12 nights total)
  • At least 20 follow-up visits
  • Up to $27,460 reimbursement for your time and commitment

Option 2:

  • 4 dosing visits
  • At least 18 follow-up visits
  • Up to $21,860 reimbursement for your time and commitment

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $27,460 *with screening reimbursement. Please see T&Cs.

Gender

Male or Female

BMI

BMI 18 - 32 kg/m2

Medical condition

Not taking any medications

Register Your Interest for The Hair Loss Screening Study

Find out if you’re eligible to join an upcoming clinical study focused on pattern hair loss (androgenetic alopecia).

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.

If you prefer to speak with our team, call us on 1300 592 174, or schedule a callback at a time that’s convenient for you.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1300 690 136 or schedule a call.


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Medical History

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow participants who are (social) smokers.

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
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Referral Information



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