The Align Study

Currently Recruiting

19 Jul 2026

Up to $8,860

Melbourne, Australia

This study is exploring a potential new medication which has been developed to target a protein called HER2. HER2 plays an important role in the growth of some types of cancer. In some cancers, changes in HER2 causes cells to grow and divide more than they should.  

While there are other treatments available which target HER2, some become less effective over time or do not reach all areas of the body, such as the brain.  

This study is evaluating a potential treatment designed to target HER2 precisely. It is hoped to help overcome some of the limitations which current treatments face.  

Apply now Speak with us 1300 758 104

Join our clinical trial

This is a first-in-human (FIH) study, meaning it is the first time the potential treatment is being tested in people. The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee. It is not known whether the study drug may cause unexpected, serious, or life-threatening side effects. While these are considered unlikely, you will be carefully monitored throughout the study and provided with prompt treatment if any such effects occur. 

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions. 

What to expect

  • Participation in a monitored clinical environment 
  • Study visits scheduled  
  • Support from a professional medical team 
  • Reimbursement for your time and commitment 

Study schedule

 

Intake 1 In-clinic stays:
19 July 2026 – 23 July 2026

30 July 2026 – 3 August 2026

16th August 2026 – 20 August 2026

 Follow-up visits:
26 July – 29 August 2026
Approx. 7 visits during this period

Study dates are subject to change. Our team will confirm details with you during the screening process.

 

Trial details

Additional eligibility

  • Weigh above 50kg 
  • Non-smokers, or smoking 5 or less cigarettes (or equivalent) per week and willing to abstain during the study 
  • Not pregnant or breastfeeding   
  • Willing to follow contraception guidelines (If applicable)  
  • Willing and able to attend all study visits and follow instructions 

Study duration

  • 2 screening visits
  • 3 x 4- night stays
  • 6  follow- up visits
  • At home dosing on 5 occasions

Study medication

The study drug is administered via oral capsule.

Ethics

The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee.

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $8,860 *with screening reimbursement.
Full details outlined in consent form.

Gender

Male, Female, Female (Post-menopausal) or Female of non-childbearing potential

BMI

BMI 18 - 32 kg/m2

Commitment

12 nights, 7 clinic visits

Medical condition

Not taking any medications

Register your interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact