The Cardio Markers Study

Currently Recruiting

15 Mar 2026 to 10 Mar 2027

Up to $18,200

Brisbane, Australia

This study is helping researchers learn more about a new investigational drug being developed to target two important markers linked with heart health: LDL cholesterol (LDL-C) and lipoprotein(a) [Lp(a)].

The aim of this early Phase 1 study is to understand how the study drug behaves in the body and to assess its safety in healthy adults. The information collected will support future research in people with elevated LDL-C or Lp(a), who may be at higher risk of cardiovascular disease.

By joining this study, you’ll be contributing to research that may help improve understanding of cholesterol, heart health, and potential future treatment options.

Apply now Speak with us

Join our clinical trial

This is a first-in-human (FIH) study, meaning it is the first time the potential treatment is being tested in people.

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions.

Join our clinical trial image

What to expect

  • Participation in a monitored clinical environment
  • Study visits scheduled
  • Support from a professional medical team
  • Payment for your time and commitment

Trial details

Study duration

3 nights stay, 18 follow-up visits

Study medication

Administered via subcutaneous injection

Additional eligibility

  • Elevated LDL-C, Lp(a) and TG levels
  • Not taking any medications within 14 days of admission (as advised by our medical team)
  • Non-smokers or smoking less than 10 cigarettes per week, less than 2 cigarettes per day.

Ethics

An independent ethics committee has approved this clinical trial.

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $18,200 *with screening reimbursement. Please see T&Cs.

Gender

Male or Female

BMI

BMI 18 - 35 kg/m2

Commitment

3 nights, 18 clinic visits

Medical condition

Not taking any medications

Register Your Interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




The phone number you have entered does not appear to be a valid active Australian phone number. Please check your details and enter a valid Australian phone number starting with +61

Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


cm

kg





















Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact