The Metabolic Adaptation Study

Currently Recruiting

2 Dec to 16 Dec 2025

Up to $5,300

This clinical study is part of a first-in-human trial focused on metabolic health. Researchers are exploring how the body responds to a new investigational capsule, and your participation could help pave the way for future therapies.

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Join our clinical trial

Every body tells a story—and yours could help researchers understand how new treatments work. 

This clinical study is part of a first-in-human trial focused on metabolic health. Researchers are exploring how the body responds to a new investigational capsule, and your participation could help pave the way for future therapies. If you’re eligible, you’ll be contributing to research that may one day support people living with conditions like obesity and type 2 diabetes. 

We’re taking the next step—testing the study drug in healthy volunteers to see how safe and tolerable it is, and how the body processes it. 

This is a first-in-human (FIH) study, meaning it’s the first time the potential treatment is being tested in people. The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee. 

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions. 

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Why participate?

  • Help advance research into a potential new treatment for metabolic disorders, such as obesity or type-2 diabetes mellitus. 
  • Be part of early-stage research that could lead to better therapies for people living with metabolic conditions. 
  • Contribute to science in a safe, controlled environment with expert medical oversight. 

Trial details

Study medication

Administered via oral capsule.

Ethics

An independent ethics committee has approved this clinical trial. 

Additional eligibility

  • Non-smokers (no tobacco or nicotine use for at least 2 months), or smoking no more than 5 cigarettes per week.  
  • Weight of at least 50kg
  • Willing to follow prescription medication guidelines, as advised by the medical staff  
  • No serious medical conditions 
  • Not pregnant or breastfeeding 
  • Willing to follow contraception guidelines (if applicable) 
  • Able to attend all study visits and follow instructions 

Study duration

10-night in-clinic stay and 1 follow-up visit

Are you a match?

Age

18 - 55 years old

Remuneration

Up to $5,300 *with screening reimbursement. Please see T&Cs.

Gender

Male or Female

BMI

BMI 20 - 35 kg/m2

Commitment

10 nights, 1 clinic visit

Register Your Interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733 or schedule a call.


What is your date of birth?
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You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



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