Melbourne Clinical Trials

The Resistance Study

The study drug is a potential new treatment for hypertension (high blood pressure).

6 nights
1 visits

Aldosterone, a naturally occurring hormone, plays an important role in managing blood pressure. When levels of aldosterone are too high, this can cause hypertension.
While effective hypertension medications are available, many people become resistant to treatment, also referred to as resistant hypertension.

This healthy volunteer study hopes to explore a medication with improved effects on reducing the hormone (aldosterone) responsible for causing resistance in currently available hypertension treatments.

The trial has been approved by an independent ethics committee and eligible participants will be reimbursed for their time.


Biological sex Male or Female
Age 18-55 years
BMI 18-32 kg/m2
Weight Weigh more than 50kg
Medical History No significant medical history
Medication Not taking any prescription medication (except for hormonal contraception)
Smoking History Non-smokers or light smokers (<5 cigarettes/week) in past 90 days