The purpose of this study is to test a potential new treatment for Invasive Pulmonary Aspergillosis (IPA), a fungal lung infection that mainly affects individuals with a weakened immune system.

5 nights
1 visits

The current approved treatment for IPA is given orally or as an IV. This study is of the same medication but administered through inhalation. This means the medication is delivered directly to where it is needed and might allow lower doses to be effective.

This inhalation method was previously tested in participants without asthma and was found to be well-tolerated. In this study we want to see how the medication is tolerated and metabolised by people with asthma, to prepare for potential future studies with people who have IPA.

The trial has been approved by an independent ethics committee and eligible participants will be reimbursed for their time.

Call us on 1800 243 733 to discuss your eligibility today!

Eligibility

Biological Sex Male or female asthmatics
Age 18-55 years old
BMI 18 – 35 kg/m²
Asthma History Documented mild asthma (including seasonal and exercise induced asthma)
Asthma Medication Currently using daily/twice daily dose of either a preventer (e.g. Seretide® or Symbicort®) or a preventer in combination with a long acting reliever (eg. Serevent Accuhaler® or Oxis Turbuhaler®).
Medication Not taking any (contraceptives, occasional Ventolin, antihistamines & eye drops allowed)
Smoking History Non smokers

Suitable Preventer Types

  • Beclometasone (HFA) (e.g Qvar) with a maximum total dose per day of 200 mcg
  • Budesonide (DPI) (e.g. Symbicort) with a maximum total dose per day of 400 mcg
  • Budesonide (nebules) (e.g. Pulmicort) with a maximum total dose per day of 500 mcg
  • Ciclesonide (HFA) (e.g. Alvesco) with a maximum total dose per day of 160 mcg
  • Fluticasone furoate (DPI) with a maximum total dose per day of 100 mcg
  • Fluticasone propionate (DPI and HFA) (e.g. Flovent & Flonase) with a maximum total dose per day of 250 mcg
  • Mometasone furoate (e.g. Asmanex) with a maximum total dose per day of 220 mcg
  • Triamcinolone (e.g. Azmacort) with a maximum total dose per day of 1000 mcg