The Sclerosis Progress Study

Currently Recruiting

30 Nov 2025 to 4 Dec 2025

Up to $5,600

We are investigating a potential treatment for Systemic sclerosis, a disease where the body’s defense system (the immune system) starts attacking healthy parts of the body by mistake. 

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Join our clinical trial

The study has been carefully designed with strict safety protocols and has been approved by an independent ethics committee. 

Before joining, you’ll receive detailed information about the study, meet with a doctor, and have the chance to ask any questions. 

We are investigating a potential treatment for Systemic sclerosis, a disease where the body’s defense system (the immune system) starts attacking healthy parts of the body by mistake. 

This causes the skin to become thick and tight, and it can also affect organs inside the body, like the lungs or heart, making them not work as well. This new treatment is important because current medications don’t always work well for everyone and can sometimes cause unwanted side effects. 

Our research is focused on finding better options that are more effective and safer, helping people with systemic sclerosis live healthier, more comfortable lives. 

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Why participate?

  • Contribute to Research that supports communities across the globe. 
  • Help Make Treatments More Inclusive and Effective 
  • Be the Reason Better Treatments Move Forward 

Trial details

Study medication

Administered via a subcutaneous injection (a small injection into the fatty tissue of your abdomen or the front part of your upper thigh).

Ethics

An independent ethics committee has approved this clinical trial.

Additional Eligibility

  • Non-smokers or smoking no more than 10 cigarettes per week, no tobacco or nicotine use during your stay. 
  • Prescription medications must be complete 14 days prior to admission (as discussed with our medical team) 
  • Flu vaccine within 12 months OR willing to receive at screening at least 2 weeks prior to dosing
  • Primary course (2) of COVID-19 + a booster vaccine within the last 12 months (received at least 2 weeks prior to dosing)
  • HEP B vaccine at least 4 weeks prior to screening
  • No serious medical conditions 
  • Not pregnant or breastfeeding 
  • Willing to follow contraception guidelines (if applicable) 
  • Able to attend all study visits and follow instructions 

Study duration

4-night in-clinic stay and 6 follow-up visits

Are you a match?

Age

18 - 65 years old

Remuneration

Up to $5,600 *with screening reimbursement. Please see T&Cs.

Gender

Male or Female

BMI

BMI 18 - 32 kg/m2

Commitment

4 nights, 6 clinic visits

Register Your Interest

This form takes around 3–5 minutes to complete. Your information will remain confidential and is used only to assess your eligibility for current or future research studies.
Step 1 of 3
Contact Information




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Nucleus Network does not currently conduct clinical trials in your state. If you would like to receive study information should this situation change, please complete and submit this form.
Personal Information

This includes registering your interest with the Centre for Clinical Studies, Q-Pharm or Nucleus Network

Please call us on 1800 243 733 or schedule a call.


What is your date of birth?
Day Month Year

You need to be at least 18 years old to participate in clinical trials.


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Step 2 of 3
Medical History

We regularly have studies that allow participants who are (social) smokers.

We define an allergy as severe if symptoms include mouth/throat/face swelling, shortness of breath or a whole-body rash, or if it required hospitalisation

We regularly have studies that allow for/require participants with asthma.



We regularly have studies that allow for/require participants with medical conditions.

Medications & Contraception Requirements

We regularly have studies that allow participants with depression that is well-managed on a stable dose of medication.

If the only prescription medication you currently use is hormonal contraception and/or Ventolin, please select No above. We regularly have studies that allow for participants who take a stable dose of prescription medication.


  • Abstinence from sex with anyone of the opposite sex for at least 2 months
  • Using a condom + your female sexual partner(s) using a separate form of birth control
  • You or your sexual partner(s) had a vasectomy/hysterectomy
  • Your sexual partner(s) are post-menopausal


Only you taking birth control or your partner(s) using a condom is not an acceptable option, but using both together is. The morning after pill is not an acceptable form of birth control.

  • Abstinence, by choice, from sex with anyone of the opposite sex for the last 2 months + remaining abstinent for at least 2 months after study participation
  • You using birth control + your male sexual partner(s) using a condom
  • You or your sexual partner(s) had a hysterectomy/vasectomy
  • You are post-menopausal



Step 3 of 3
Study Preferences

While longer studies generally have a higher reimbursement, there are also studies with multiple short stays that have high reimbursements.
Referral Information



Consent to Information Use and Future Contact