It’s time to tip the scales

Potential new treatments for weight and metabolic health are currently being studied in clinical trials.

If your BMI is 32 or higher, you may be eligible to participate in a research study now recruiting. By taking part, you could help researchers learn how new medicines work and contribute to the development of future treatment options.

Who may be eligible?

You may be eligible to participate if you:

Are aged 18 to 65

Have a BMI around 32 or higher

Are generally in good health

Are interested in contributing to clinical research

Eligibility requirements vary between studies and are confirmed during the screening process.

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Calculate your body mass index (BMI)

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Why this research is important

Carrying extra weight can affect health in many ways.

A higher Body Mass Index (BMI) is associated with an increased risk of conditions such as:

Heart disease

Type 2 diabetes

High blood pressure

Sleep apnoea

Fatty liver disease

Joint problems

For many people, maintaining a healthy weight is not always straightforward. Lifestyle plays a role, but biological factors such as hormones, metabolism and genetics also influence how the body regulates hunger and energy balance.

Because of this, researchers continue to explore medical approaches that may help people manage weight alongside healthy diet and lifestyle choices.

Weight is influenced by more than willpower

For many years, discussions about weight focused mainly on lifestyle factors. Research now shows that body weight is also influenced by biological systems that regulate appetite, metabolism and energy balance. Hormones signal when we feel hungry or full, the brain helps control appetite, and metabolism affects how the body stores and uses energy. Because these systems work differently for each person, weight regulation can vary from one individual to another.

This growing understanding has led to the development of new medicines designed to work with the body’s natural signalling pathways. Clinical trials help researchers study how these medicines behave in the body and whether they may become part of future treatment options.

See studies recruiting now

Rapid progress in metabolic medicine

In recent years, medicines such as GLP-1 therapies have changed how doctors approach weight management and metabolic health. These medicines work with the body’s natural signalling systems to influence appetite, blood sugar levels and energy balance.

Researchers are continuing to study new molecules and mechanisms that may further improve outcomes for people living with obesity and related cardio-metabolic conditions.

The weight management medicines people talk about today all began in early clinical trials involving volunteers who chose to take part. Clinical studies help researchers understand how potential treatments behave in the body and whether they may become part of future care.

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How clinical trials work

Before a medicine is studied in people, it has already gone through years of laboratory and pre-clinical research.

Safety testing is completed.

Regulatory authorities review the data.

Independent ethics committees approve the study protocol.

Human trials help confirm how medicines behave in the body and provide the information needed to guide safe use.

Studies are carefully structured, closely monitored and conducted under strict regulatory oversight.

For many participants, being part of this process means contributing to something that may benefit people well beyond their own community.

Why people participate

People choose to take part in clinical trials for a range of reasons. Some are interested in contributing to medical research, while others are curious to learn more about how clinical trials work.

Many participants also appreciate the reimbursement provided for their time and commitment. For many, taking part offers the added satisfaction of knowing they have contributed to research that may help improve health outcomes for others in the future.

Global impact

Medicine development is a global process.

Data generated in clinical trials contributes to regulatory submissions and treatment development around the world.

The research conducted here helps build the evidence needed for medicines that may one day be used internationally.

Participation in a clinical trial means contributing to research that may ultimately help patients far beyond this clinic.

Browse available studies

Why are participants reimbursed?

Taking part in a clinical trial requires time and commitment.

Participants may attend screening appointments, spend time in the clinic and return for follow-up visits.

Reimbursement recognises that time and involvement.

It is not payment for risk. It reflects the value of a participant’s time and their contribution to the study.

For many people, participation offers a practical way to be compensated for their time while also contributing to medical research.

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Studies currently recruiting

We are currently enrolling participants with a BMI around 32 or higher at our research clinics in Melbourne, Brisbane and Sydney.

Each study has its own eligibility criteria and time commitments. Advances in metabolic medicine rely on people who choose to take part in clinical research. If you’re interested in learning more, explore the studies that are currently recruiting to see whether one may be suitable for you.

Browse current studies