Brisbane Clinical Trials

The Inhibitor Study

The purpose of the study is to investigate a potential new treatment for complement mediated diseases.

9 + 2 x 1 + 5 nights
7 + 2 vaccine visits

The complement system is a part of the immune system. When this malfunctions, it can cause autoimmune diseases. Diseases related to the regulation of the complement system include autoimmune diseases such as lupus and rheumatoid arthritis.

There are already several similar treatments that block specific elements of the complement system to treat these diseases, but there is an ongoing need for new & improved treatments.

For this part of the study, we require participants who are eligible to receive
Bexsero, Menveo and Pneumovax vaccinations in preparation for completing
the full study at a later date.

The trial has been approved by an independent ethics committee and eligible participants will be reimbursed for their time.

Eligibility

Biological Sex Healthy males and females that received at least 1 Bexsero, Menveo or Pneumovax in last 2.5 years
Age 18 - 55 years old
BMI 18 - 32kg/m²
Medical History No significant medical history
Medications Not taking any medication
Smoking History Non-smokers or smokers who smoke less than 10 per week